Solifenacin causes less dry mouth than oxybutynin in OAB
نویسندگان
چکیده
منابع مشابه
Solifenacin is effective for the treatment of OAB dry patients: a pooled analysis.
OBJECTIVE The aim of this analysis was to determine the effects of solifenacin in patients considered overactive bladder (OAB) dry at baseline. METHODS This was a pooled analysis of 4 randomized, placebo-controlled 12-week, phase 3 studies. Patients received placebo or solifenacin 10 mg once daily (2 studies), or placebo or solifenacin 5 mg or 10 mg once daily (2 studies). A subgroup of patie...
متن کاملOxybutynin: dry days for patients with hyperhidrosis.
We report the case of a 56-year-old postmenopausal woman who was referred to our Endocrinology Outpatient Clinic because of severe hyperhidrosis. She had a four-year history of excessive sweating of her face and upper body. On presentation no sweating could be documented. Physical examination was also unremarkable. It appeared that five days earlier her general practitioner had prescribed oxybu...
متن کاملTransdermal drug delivery treatment for overactive bladder.
Overactive bladder is commonly treated with oral anticholinergic drugs such as oxybutynin chloride. Although oral anticholinergic agents have been effective in controlling urinary urgency and incontinence, adverse events, particularly dry mouth, often cause patients to discontinue oral therapy and to endure incontinence. Oxybutynin can be delivered transcutaneously, maintaining the efficacy of ...
متن کاملRe: randomised, multicentre, placebo-controlled, double-blind crossover study investigating the effect of solifenacin and oxybutynin in elderly people with mild cognitive impairment: the SENIOR study.
BACKGROUND Compared with younger people, the elderly are more likely to suffer from overactive bladder (OAB) and to have other chronic conditions that affect physical or cognitive function. Despite this, there are few data on the cognitive safety of antimuscarinic agents in older patients and none that examine the effect of these agents on those with mild cognitive impairment (MCI). OBJECTIVE...
متن کاملClinical Medicine Insights: Therapeutics
Overactive bladder (OAB), a bothersome condition that is frequently associated with incontinence, commonly affects middleaged and elderly people. OAB not only has a negative effect on physical and mental well-being but also accounts for billions of dollars in health care costs and lost productivity. Although OAB can be treated effectively with muscarinic acetylcholine receptor antagonists, thes...
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ژورنال
عنوان ژورنال: Nature Reviews Urology
سال: 2010
ISSN: 1759-4812,1759-4820
DOI: 10.1038/nrurol.2010.73